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Lipopolysaccharides (脂多糖; LPS)

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Lipopolysaccharides (LPS) 脂多糖是從革蘭氏陰性菌外膜的外葉中提取的內(nèi)DU素,由一個(gè)抗原 O- 特異性鏈、一個(gè)he心寡糖和脂質(zhì) A 構(gòu)成,是高度免疫原性抗原可以增強(qiáng)免疫反應(yīng)。本產(chǎn)品來(lái)源于大腸桿菌 O55:B5。

貨號(hào):HY-D1056
參數(shù)品牌:MCE
產(chǎn)品參數(shù)
品牌:MCE
型號(hào):HY-D1056
起訂量:1
規(guī)格::5mg
價(jià)格::¥1200
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Lipopolysaccharides (Synonyms: 脂多糖; LPS)

Lipopolysaccharides (Synonyms: 脂多糖; LPS)-杭州昊鑫,Lipopolysaccharides (LPS) 脂多糖是從革蘭氏陰性菌外膜的外葉中提取的內(nèi)DU素,由一個(gè)抗原 O- 特異性鏈、一個(gè)he心寡糖和脂質(zhì) A 構(gòu)成,是高度免疫原性抗原可以增強(qiáng)免疫反應(yīng)。本產(chǎn)品來(lái)源于大腸桿菌 O55:B5。


生物活性

Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consists of an antigen O-specific chain, a core oligosaccharide and lipid A[3]. Lipopolysaccharides is a highly immunogenic antigen which can enhance immune responses[4][5]. This product is derived from Escherichia coli O55:B5.


Clinical Trial

NCT NumberSponsorConditionStart DatePhase
NCT02876601Bernd Jilma|Medical University of Vienna
Healthy Volunteers|Endotoxemia
April 18, 2017Phase 4
NCT04233593Yale University
Healthy
March 25, 2014Phase 1
NCT01081392Centre Hospitalier Universitaire Brugmann
Inflammation
January 2010Not Applicable


中文名稱:脂多糖


結(jié)構(gòu)分類:Saccharides


來(lái)源:surface of Gram-negative bacteria


運(yùn)輸條件:Room temperature in continental US; may vary elsewhere


儲(chǔ)存方式:

Powder-20°C3 years

4°C2 years
In solvent-80°C6 months

-20°C1 month


溶解性數(shù)據(jù):H2O : 5 mg/mL (Need ultrasonic)


參考文獻(xiàn)

[1]. Rietschel ET, et al. Bacterial endotoxin: molecular relationships of structure to activity and function. FASEB J. 1994 Feb;8(2):217-25.

[2]. Kabanov DS, et al. Structural analysis of lipopolysaccharides from Gram-negative bacteria. Biochemistry (Mosc). 2010 Apr;75(4):383-404.

[3]. Heinrichs DE, et al. Molecular basis for structural diversity in the core regions of the lipopolysaccharides of Escherichia coli and Salmonella enterica. Mol Microbiol. 1998 Oct;30(2):221-32.

[4]. Kajiwara Y, et al. A critical role for human caspase-4 in endotoxin sensitivity. J Immunol. 2014 Jul 1;193(1):335-43.

[5]. Lai HT, et al. Effects of repeated intratracheally administered lipopolysaccharide on primary and secondary specific antibody responses and on body weight gain of broilers. Poult Sci. 2011 Feb;90(2):337-51.


Lipopolysaccharides (脂多糖; LPS)
Lipopolysaccharides (脂多糖; LPS)

Lipopolysaccharides (脂多糖; LPS)

分享到微信

×
Lipopolysaccharides (LPS) 脂多糖是從革蘭氏陰性菌外膜的外葉中提取的內(nèi)DU素,由一個(gè)抗原 O- 特異性鏈、一個(gè)he心寡糖和脂質(zhì) A 構(gòu)成,是高度免疫原性抗原可以增強(qiáng)免疫反應(yīng)。本產(chǎn)品來(lái)源于大腸桿菌 O55:B5。

貨號(hào):HY-D1056
品牌:MCE
型號(hào):HY-D1056
起訂量:1
規(guī)格::5mg
價(jià)格::¥1200
15906629305
在線客服
產(chǎn)品詳情

Lipopolysaccharides (Synonyms: 脂多糖; LPS)

Lipopolysaccharides (Synonyms: 脂多糖; LPS)-杭州昊鑫,Lipopolysaccharides (LPS) 脂多糖是從革蘭氏陰性菌外膜的外葉中提取的內(nèi)DU素,由一個(gè)抗原 O- 特異性鏈、一個(gè)he心寡糖和脂質(zhì) A 構(gòu)成,是高度免疫原性抗原可以增強(qiáng)免疫反應(yīng)。本產(chǎn)品來(lái)源于大腸桿菌 O55:B5。


生物活性

Lipopolysaccharides (LPS) is an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consists of an antigen O-specific chain, a core oligosaccharide and lipid A[3]. Lipopolysaccharides is a highly immunogenic antigen which can enhance immune responses[4][5]. This product is derived from Escherichia coli O55:B5.


Clinical Trial

NCT NumberSponsorConditionStart DatePhase
NCT02876601Bernd Jilma|Medical University of Vienna
Healthy Volunteers|Endotoxemia
April 18, 2017Phase 4
NCT04233593Yale University
Healthy
March 25, 2014Phase 1
NCT01081392Centre Hospitalier Universitaire Brugmann
Inflammation
January 2010Not Applicable


中文名稱:脂多糖


結(jié)構(gòu)分類:Saccharides


來(lái)源:surface of Gram-negative bacteria


運(yùn)輸條件:Room temperature in continental US; may vary elsewhere


儲(chǔ)存方式:

Powder-20°C3 years

4°C2 years
In solvent-80°C6 months

-20°C1 month


溶解性數(shù)據(jù):H2O : 5 mg/mL (Need ultrasonic)


參考文獻(xiàn)

[1]. Rietschel ET, et al. Bacterial endotoxin: molecular relationships of structure to activity and function. FASEB J. 1994 Feb;8(2):217-25.

[2]. Kabanov DS, et al. Structural analysis of lipopolysaccharides from Gram-negative bacteria. Biochemistry (Mosc). 2010 Apr;75(4):383-404.

[3]. Heinrichs DE, et al. Molecular basis for structural diversity in the core regions of the lipopolysaccharides of Escherichia coli and Salmonella enterica. Mol Microbiol. 1998 Oct;30(2):221-32.

[4]. Kajiwara Y, et al. A critical role for human caspase-4 in endotoxin sensitivity. J Immunol. 2014 Jul 1;193(1):335-43.

[5]. Lai HT, et al. Effects of repeated intratracheally administered lipopolysaccharide on primary and secondary specific antibody responses and on body weight gain of broilers. Poult Sci. 2011 Feb;90(2):337-51.


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