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Pyrroloquinoline quinone (Synonyms: 吡咯喹啉醌; PQQ; Methoxatin)
Pyrroloquinoline quinone (PQQ) 是氧化還原輔助因子，一種陰離子型氧化還原循環(huán)原醌。Pyrroloquinoline quinone 最初是從嗜甲基細(xì)菌的培養(yǎng)物中分離的，也存在于哺乳動(dòng)物的組織。Pyrroloquinoline quinone 是哺乳動(dòng)物的必需營(yíng)養(yǎng)素，對(duì)免疫功能很重要。
生物活性
Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function[1][2].
IC50 & Target[1]
Human Endogenous Metabolite
體外研究(In Vitro)
Mouse pups born to and nursing from Pyrroloquinoline quinone (PQQ)-deprived dams have a compromised immune response as well as alopecia, a hunched posture, and a susceptibility to aortic aneurysms[2].
分子量：330.21
Formula：C14H6N2O8
CAS 號(hào)：72909-34-3
中文名稱：吡咯喹啉醌；吡咯并喹啉苯醌
來源：prokaryotes
運(yùn)輸條件：Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式：
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
溶解性數(shù)據(jù)
H2O : 1 mg/mL (3.03 mM; ultrasonic and warming and heat to 60°C)
DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)
| 濃度溶劑體積質(zhì)量 | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.0284 mL | 15.1419 mL | 30.2838 mL |
| 5 mM | --- | --- | --- |
| 10 mM | --- | --- | --- |
請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；一旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲(chǔ)備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 儲(chǔ)存時(shí)，請(qǐng)?jiān)?6 個(gè)月內(nèi)使用，-20°C 儲(chǔ)存時(shí)，請(qǐng)?jiān)?1 個(gè)月內(nèi)使用。
參考文獻(xiàn)
在線客服客服一Pyrroloquinoline quinone (Synonyms: 吡咯喹啉醌; PQQ; Methoxatin)
Pyrroloquinoline quinone (PQQ) 是氧化還原輔助因子，一種陰離子型氧化還原循環(huán)原醌。Pyrroloquinoline quinone 最初是從嗜甲基細(xì)菌的培養(yǎng)物中分離的，也存在于哺乳動(dòng)物的組織。Pyrroloquinoline quinone 是哺乳動(dòng)物的必需營(yíng)養(yǎng)素，對(duì)免疫功能很重要。
生物活性
Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function[1][2].
IC50 & Target[1]
Human Endogenous Metabolite
體外研究(In Vitro)
Mouse pups born to and nursing from Pyrroloquinoline quinone (PQQ)-deprived dams have a compromised immune response as well as alopecia, a hunched posture, and a susceptibility to aortic aneurysms[2].
分子量：330.21
Formula：C14H6N2O8
CAS 號(hào)：72909-34-3
中文名稱：吡咯喹啉醌；吡咯并喹啉苯醌
來源：prokaryotes
運(yùn)輸條件：Room temperature in continental US; may vary elsewhere.
儲(chǔ)存方式：
| Powder | -20°C | 3 years |
|---|---|---|
| 4°C | 2 years | |
| In solvent | -80°C | 6 months |
| -20°C | 1 month |
溶解性數(shù)據(jù)
H2O : 1 mg/mL (3.03 mM; ultrasonic and warming and heat to 60°C)
DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)
| 濃度溶劑體積質(zhì)量 | 1 mg | 5 mg | 10 mg |
|---|
| 1 mM | 3.0284 mL | 15.1419 mL | 30.2838 mL |
| 5 mM | --- | --- | --- |
| 10 mM | --- | --- | --- |
請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；一旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。
儲(chǔ)備液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 儲(chǔ)存時(shí)，請(qǐng)?jiān)?6 個(gè)月內(nèi)使用，-20°C 儲(chǔ)存時(shí)，請(qǐng)?jiān)?1 個(gè)月內(nèi)使用。
參考文獻(xiàn)
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