PEG300  (Synonyms: 聚乙二醇; Polyethylene glycol 300)

PEG300 (Polyethylene glycol 300)，分子量為300的中性聚合物，由乙二醇重復(fù)單元形成的水溶性、低免疫原性和生物相容性聚合物。

生物活性

PEG300 (Polyethylene glycol 300), a neutral polymer of molecular weight 300, is a water-soluble, low immunogenic and biocompatible polymer formed by repeating units of ethylene glycol^[1][2].

體外研究(In Vitro)

The FDA has approved polyethylene glycol (PEG) for use as a vehicle or base in foods, cosmetics and pharmaceuticals, including injectable, topical, rectal and nasal formulations. PEG shows little toxicity, and is eliminated from the body intact by either the kidneys (for PEGs < 30 kDa) or in the faeces (for PEGs > 20 kDa). PEG lacks immunogenicity, and antibodies to PEG are generated in rabbits only if PEG is combined with highly immunogenic proteins^[3].

體內(nèi)研究(In Vivo)

Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs). 
The final concentration of PEG300 can go up to 50% in the formulations for intravenous and intramuscular injection without any toxic effects. When administered orally, the highest concentration of PEG300 can reach up to 90%^[4][5].

分子量：300.00

性狀：Liquid

CAS 號：25322-68-3

中文名稱：聚乙二醇

運輸條件

Room temperature in continental US; may vary elsewhere.

儲存方式

4°C, sealed storage, away from moisture

溶解性數(shù)據(jù)

In Vitro: 

參考文獻